{"id":1838,"date":"2017-10-06T11:02:36","date_gmt":"2017-10-06T09:02:36","guid":{"rendered":"http:\/\/www.hopital-marmottan.fr\/wordpress\/?p=1838"},"modified":"2018-08-24T10:34:07","modified_gmt":"2018-08-24T08:34:07","slug":"publication-baclophone","status":"publish","type":"post","link":"https:\/\/www.hopital-marmottan.fr\/wordpress\/?p=1838","title":{"rendered":"[Publication] Baclophone"},"content":{"rendered":"<p><a href=\"http:\/\/www.chru-lille.fr\/media\/communique-presse\/BACLOPHONE_Rapport%20N1_Sept2017.pdf\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-1840\" src=\"http:\/\/www.hopital-marmottan.fr\/wordpress\/wp-content\/uploads\/2017\/11\/baclophone.png\" alt=\"\" width=\"387\" height=\"130\" srcset=\"https:\/\/www.hopital-marmottan.fr\/wordpress\/wp-content\/uploads\/2017\/11\/baclophone.png 387w, https:\/\/www.hopital-marmottan.fr\/wordpress\/wp-content\/uploads\/2017\/11\/baclophone-300x101.png 300w\" sizes=\"auto, (max-width: 387px) 100vw, 387px\" \/><\/a>BACLOPHONE est une \u00e9tude pharmaco-\u00e9pid\u00e9miologique consistant en un suivi t\u00e9l\u00e9phonique \u00e9troit des patients trait\u00e9s par baclof\u00e8ne pour alcoolod\u00e9pendance, au cours de leur premi\u00e8re ann\u00e9e de traitement. L\u2019objectif principal de BACLOPHONE est d\u2019observer l\u2019imputabilit\u00e9 du baclof\u00e8ne dans les \u00e9v\u00e9nements ind\u00e9sirables (EI) pouvant survenir en cours de traitement. La premi\u00e8re partie de l&rsquo;\u00e9tude, bas\u00e9e sur 104 participants pendant un an, a \u00e9t\u00e9 rendue publique.<\/p>\n<p>Ces donn\u00e9es montrent\u00a0 un niveau de responsabilit\u00e9 tr\u00e8s variable du baclof\u00e8ne dans la survenue de probl\u00e8mes de s\u00e9curit\u00e9 en cours de traitement. Elles sugg\u00e8rent \u00e9galement que certains \u00e9v\u00e9nements ind\u00e9sirables imputables au baclof\u00e8ne surviennent en cas de prescription ou de prise du traitement ne respectant par les recommandations officielles, notamment lorsque les variations de posologies sont trop rapides. Ce dernier point souligne la n\u00e9cessit\u00e9 d\u2019une bonne connaissance des modalit\u00e9s de prescription du traitement par les m\u00e9decins prescripteurs et les patients, et l\u2019int\u00e9r\u00eat de renforcer la formation des prescripteurs et l\u2019information des patients recevant ce traitement.<\/p>\n<p><a href=\"http:\/\/www.chru-lille.fr\/media\/communique-presse\/BACLOPHONE_Rapport%20N1_Sept2017.pdf\">Lire l&rsquo;int\u00e9gralit\u00e9 du rapport <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>BACLOPHONE est une \u00e9tude pharmaco-\u00e9pid\u00e9miologique consistant en un suivi t\u00e9l\u00e9phonique \u00e9troit des patients trait\u00e9s par baclof\u00e8ne pour alcoolod\u00e9pendance, au cours de leur premi\u00e8re ann\u00e9e de traitement. L\u2019objectif principal de BACLOPHONE est d\u2019observer l\u2019imputabilit\u00e9 du baclof\u00e8ne dans les \u00e9v\u00e9nements ind\u00e9sirables (EI) &hellip; <a href=\"https:\/\/www.hopital-marmottan.fr\/wordpress\/?p=1838\">Continuer la lecture <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[497],"tags":[42,521,520,26,522,173],"class_list":["post-1838","post","type-post","status-publish","format-standard","hentry","category-publications","tag-alcool","tag-bacloflene","tag-baclophone","tag-enquete","tag-evenement-indesirable","tag-traitement"],"_links":{"self":[{"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/1838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1838"}],"version-history":[{"count":1,"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/1838\/revisions"}],"predecessor-version":[{"id":1841,"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=\/wp\/v2\/posts\/1838\/revisions\/1841"}],"wp:attachment":[{"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1838"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hopital-marmottan.fr\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}